| abstract |
The present invention provides a bARE composition that is stable upon storage and has long-term activity over time. The composition contains substantially complete bARE class protein. In one embodiment, the composition also contains a stabilizer, which is a charged amino acid or analog thereof. In another embodiment, the stabilizer is arginine or arginine phosphate. The arginine or arginine phosphate is present in an amount from about 100 mM to about 400 mM. In further embodiments, the composition contains an uncharged substance or analog thereof, or contains a zwitterionic substance. This zwitterionic substance is a zwitterionic surfactant, which is 3- (3-cholamidopropyl) -dimethylammonio-1-propanesulfonate (CHAPS). [Selection figure] None |