| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b7e87f29e0db9416800cab4f60f6c468
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9072b28d37bc04a9c1f43327bac4d033 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-042
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-44 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-451
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4035 |
| filingDate |
2008-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0295764ab75ada96f3001d8cab8aa8b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01bc586da73e766e7ada42a7c884870a |
| publicationDate |
2011-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2011125218-A |
| titleOfInvention |
Method for predicting drug sensitivity of phenylalanine derivatives in diabetic patients |
| abstract |
[Solution] Based on a polymorphism related to the effectiveness of an antidiabetic agent comprising a phenylalanine derivative drug (for example, nateglinide) as an active ingredient, a diabetic patient who responds to the phenylalanine derivative drug is selected and determined. Provide a method. In addition, a drug effective for treating diabetes is provided. [Means] An indicator is that a diabetic patient has the following GENOTYPE for at least one of the genes (1) to (3): Gene (gene polymorphism) : GENOTYPE (1) GYS1 (A260G): GG or AG (2) EPHX2 (G860A): AA or AG (3) CD14 (T-159C): CC or CT The drug of the present invention is a drug for diabetic patients having the above GENOTYPE, and comprises a phenylalanine derivative-based drug as an active ingredient. [Selection figure] None |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016067323-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015080464-A |
| priorityDate |
2008-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |