http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011109936-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32db58f74a0dc0eb7fb0fb75ce6dfa95 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate | 2009-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90e666eb86231c3cbd7232a8fce51a58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0afc6eaea076a2d14146845625efb36c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e917c04f88000c5bfaf4eeae1f2fb1df |
| publicationDate | 2011-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2011109936-A |
| titleOfInvention | Chemically modified ribonucleotide synthesis and its gene expression inhibitory effect |
| abstract | Provided is a siRNA that is a double-stranded RNA having 21 to 27 bases that suppresses the expression of a target gene used in RNA interference or the like, and has a high gene suppression effect. Also provided is an efficient gene expression suppression method using the siRNA. [MEANS FOR SOLVING PROBLEMS] A low molecular weight compound having an unsaturated hydrocarbon compound as a basic skeleton is easily and efficiently chemically modified into ribonucleotides by a known phosphoramidite method or an active esterification method using a succinimide linker. An efficient gene expression suppression technique represented by the above-mentioned siRNA production means and RNA interference method using the same. [Selection figure] None |
| priorityDate | 2009-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.