| abstract |
Powerful cannabinoid (CB 1 ) receptor antagonists, CB 1 receptor agonists shown to be beneficial for the treatment of psychiatric and neurological disorders, and other diseases involving cannabinoid CB 1 neurotransmission or CB 1 provides the receptor partial agonists are thiazole derivatives. A compound represented by the following general formula (1): [Wherein, R represents a halogen atom, and R 1 to R 4 represent specific substituents. ] [Selection figure] None |