abstract |
There is a need for polynucleotide compositions that have an inhibitory effect on specific target polynucleotide sequences present in mammalian cells. The present invention relates to a multi-target, comprising two or more different double-stranded RNA sequences that are substantially homologous and complementary to two or more sequences of at least one target gene. The problem described above is solved by using partially double-stranded RNA molecules. [Selection figure] None |