abstract |
Disclosed is a drug for use in the treatment or prevention of RSV infection. It has been found that benzodiazepine derivatives of formula (I) and their pharmaceutically acceptable salts are effective against RSV. Formula (I): [Wherein, R 1 represents aryl or heteroaryl, R 2 represents hydrogen, R 3 represents various substituents, n is 0 to 3, R 4 represents hydrogen, R 5 represents aryl, Heteroaryl, carbocyclyl, heterocyclyl, aryl- (C 1-6 alkyl)-, heteroaryl- (C 1-6 alkyl)-, carbocyclyl- (C 1-6 alkyl)-, heterocyclyl- (C 1-6 alkyl) -, Aryl-C (O) -C (O)-, heteroaryl-C (O) -C (O)-, carbocyclyl-C (O) -C (O)-, heterocyclyl-C (O) -C (O) — or —XR 6 or the like is represented. ] [Selection figure] None |