| abstract |
The present invention provides a specified TNF-α inhibitor for use in a pharmaceutical composition for treating spinal cord injury as nerve root injury caused by the release of TNF-α. Metalloproteinase inhibitors other than methylprenisone, tetracyclines including chemically modified tetracyclines, quinolones, corticosteroids, thalidomides, lazaloids, pentoxyphyllins, hydroxamic acid derivatives, carbocyclic acids, natoppyran, Soluble cytokine receptor, monoclonal antibody against TNF-α, amrinone, pimobendan, vesnarinone, phosphodiesterase III inhibitor, lactoferrin and lactoferrin-derived homologue and TNF-α as a form of addition salt thereof or melatonin Inhibitor. [Selection figure] None |