| abstract |
There is a need for antibiotics that represent a new class of compounds that have not previously been used to treat bacterial infections. The present invention relates to a compound that inhibits bacterial gyrase and / or TopoIV and a pharmaceutical composition containing the compound. These compounds and their compositions are useful in treating or reducing the severity of bacterial infections. In particular, the compounds of the invention treat or severely treat urinary tract infections, pneumonia, prostatitis, skin and soft tissue infections, intraperitoneal infections, bloodstream infections, or infections of febrile neutropenic patients. Useful to reduce the degree. Accordingly, the present invention also relates to a method of treating a bacterial infection in a mammal. Formula (I). [Selection figure] None |