http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011045291-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82787c2fee17b0b0eb295d5af7d2325f |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2009-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efbaf38eefcc4aa8a9f1fc165ecaafff |
| publicationDate | 2011-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2011045291-A |
| titleOfInvention | Dexamethasone-induced protein gene region, anticancer drug resistance discrimination kit, anticancer drug sensitivity recovery method, anticancer drug composition, siRNA, apoptosis recovery composition |
| abstract | A gene region of a marker for determining resistance to an anticancer drug is provided. [Solution] An anticancer drug resistance determination method is provided. A novel function of the dexamethasone-induced protein gene was identified. In this dexamethasone-induced protein gene, the promoter region is methylated. When the expression of dexamethasone-induced protein decreases due to this methylation, apoptosis due to a caspase cascade is suppressed. For this reason, the present invention is characterized by detecting methylation of the dexamethasone-induced protein gene region of cancer cells and determining that it is resistant to an anticancer drug when the methylation is performed. [Selection] Figure 1 |
| priorityDate | 2009-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 184.