| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e9c55cbd632f124625c19c848aaffd9c |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 |
| filingDate |
2010-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2928506ff4e3afddb663529696471b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f402b8d5e90020a03b868c5fd9a5bce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_582bb1b7108d7660556fbb81bbe80f83
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d2d4d8acf8ffffa6f8a316d0efce66e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e206441787bd34e8fa53e140ec6a42a |
| publicationDate |
2011-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2011024593-A |
| titleOfInvention |
Anti-CD4 antibody homologues useful for the prevention and treatment of AIDS, ARC and HIV infection |
| abstract |
The present invention provides an anti-CD4 antibody capable of effectively blocking HIV-induced syncytium formation without significantly blocking the binding of HIV gp120 to human CD4, and is induced by HIV between CD4 + cells. Providing 5A8 mimetic peptide or half-peptide compound that inhibits syncytium formation and / or inhibits HIV infection of CD4 + cells. An anti-CD4 antibody is provided that can effectively block HIV-induced syncytium formation without significantly blocking the binding of HIV gp120 to human CD4. Further provided are 5A8 mimetic peptide or half peptide compounds that inhibit HIV-induced syncytium formation between CD4 + cells, and 5A8 mimetic peptide or half peptide compounds that inhibit HIV infection of CD4 + cells. [Selection figure] None |
| priorityDate |
1990-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |