| abstract |
A zwitterionic organic polymer monolith column having high resolution, high versatility, and suitable for separation and analysis of polar compounds that can also be used as a separation medium for HILIC, and its A manufacturing method is provided. A monomer comprising a reactive monomer having a zwitterionic functional group of an ammonium group and a sulfo group, or a functional group that can be converted into an ammonium group and / or a sulfo group, a crosslinking monomer, and a pore-forming agent. The solution is injected into the column, and radiation polymerization is performed in the column. The polymer skeleton having the zwitterionic functional functional group of ammonium group and sulfo group is used as the stationary phase, and the stationary phase and the void are both three-dimensional. A method for producing a zwitterionic organic polymer monolithic column comprising obtaining a porous body having a network structure communicating with the zwitterionic organic polymer monolithic column obtained by the production method. [Selection] Figure 1 |