http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011012018-A

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filingDate 2009-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5aff64c6f7957dd901258dad8157a12b
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publicationDate 2011-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2011012018-A
titleOfInvention Pharmaceutical composition for oral administration of paroxetine hydrochloride hydrate with suppressed decay delay
abstract An object of the present invention is to provide a pharmaceutical composition of paroxetine hydrochloride hydrate with suppressed decay delay. [Solution] Paroxetine hydrochloride hydrate; At least one excipient selected from the group consisting of lactose, sucrose, D-mannitol, corn starch, partially pregelatinized starch, crystalline cellulose, anhydrous calcium hydrogen phosphate and calcium hydrogen phosphate hydrate; and carmellose At least one disintegrant selected from the group consisting of calcium, low substituted hydroxypropylcellulose and sodium carboxymethyl starch; A pharmaceutical composition for oral administration comprising a) selecting anhydrous calcium hydrogen phosphate as an excipient and selecting at least any one of the disintegrants; b) At least any one of the excipients is selected, and carmellose calcium or low-substituted hydroxypropylcellulose or both are selected as disintegrants. A granulated product obtained by coating paroxetine hydrochloride hydrate with hypromellose may be mixed with calcium hydrogen phosphate as an excipient and sodium carboxymethyl starch as a disintegrant, and tableted. [Selection figure] None
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115350157-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014129239-A
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