| abstract |
A series of N-substituted oxindole derivatives of formula I, or pharmaceutically acceptable salts thereof. The pharmaceutical composition comprises an effective amount of the compound (alone or together with one or more therapeutically active compounds) and a pharmaceutically acceptable carrier. (Eg, acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain, urinary incontinence, pruritus, allergic dermatitis, epilepsy, diabetic neuropathy, irritable bowel syndrome, depression, anxiety, multiple Methods of treatment of conditions associated with or caused by calcium channel activity (including sclerosis, sleep disorders, bipolar disorder and stroke) include an effective amount of the compound alone, or one or more other Administration with any of the therapeutically active compounds. |