abstract |
The present invention relates to pyrazolo-pyrazine derivatives of general formula (I) Wherein Z, R 1 , R 2 , R 3 and R 4 groups represent variable groups, X is a sulfur atom or selenium atom, and n is an integer equal to 1 or 2. They are particularly important for the treatment of diseases involving heterotrimeric G proteins. The present invention also relates to pharmaceutical compositions comprising the product and their use to produce a drug. |