| abstract |
Methods of treating inflammatory conditions, diseases and disorders are provided. The method includes, for example, contacting or administering to a subject a sufficient amount of a LIGHT inhibitor to treat the inflammatory condition, disease and disorder. LIGHT (p30 polypeptide) inhibitors include LIGHT, LTβR (lymphotoxin beta receptor), a partial sequence of HVEM (herpesvirus entry mediator) or antibodies that bind to LIGHT (p30 polypeptide), LTβR or HVEM. Such LIGHT inhibitors are used, for example, for lung or airway inflammation such as asthma or airway remodeling, asthma, respiratory or interstitial or pulmonary or fibrotic diseases or disorders. |