| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| filingDate |
2008-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2010-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2010538030-A |
| titleOfInvention |
Use of GIP for the treatment of disorders associated with dysfunctional synaptic transmission |
| abstract |
The present invention provides a gastric inhibitory polypeptide useful for prophylactically preventing, ameliorating or reversing the cognitive decline associated with these types of disorders by increasing (or maintaining) LTP of synaptic transmission. Relates to peptides comprising at least 12 amino acid residues from the N-terminus of the analog. Moreover, maintenance of LTP is useful in preventing neurological diseases by delaying the onset of cognitive process damage, not only in cognitive decline caused by neurodegeneration, but also in trauma or aging It turns out to be useful for treating the accompanying dysfunctional cognitive process. In addition, the peptides and analogs of the present invention are useful for improving the alteration of cognitive function associated with hyperexcitatory disorder by reducing high levels of LTP of synaptic transmission. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018104423-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018104424-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11555069-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018124010-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7165495-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7165496-B2 |
| priorityDate |
2007-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |