| abstract |
The positive ionic lipid of the present invention is used for the production of nucleic acids or negative ionic bioactive protein mediators. The cationic lipid of the present invention has a simple production and purification process and high economic efficiency during mass production. In addition, the nucleic acid or protein carrier containing the cationic lipid of the present invention is a nucleic acid pharmaceutical such as deoxyribonucleic acid, ribonucleic acid, small interfering RNA, antisense oligonucleotide, and nucleic acid aptamer to be transmitted into cells. In addition to notably enhancing the efficiency of transporting negatively ionic proteins possessing bioactivity and bioactivity into cells, they are useful in applications that reduce the cytotoxicity and enhance the therapeutic efficacy of nucleic acid or protein materials. It is done. |