http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010536918-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| filingDate | 2008-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2010536918-A |
| titleOfInvention | Substituted azabicyclo [4.1.0] heptane compounds for use as monoamine reuptake inhibitors |
| abstract | The present invention relates to novel compounds of formula (I) ', a pharmaceutically acceptable salt thereof, prodrug or solvate thereof [wherein, R 1 is hydrogen or C 1-4 alkyl; R 2 is An α or β naphthyl group optionally substituted by one or two groups R 8 which are the same or different; R 8 is selected from the group consisting of halogen, cyano, C 1-4 alkyl R 5 is hydrogen or C 1-4 alkyl; R 6 is hydrogen or C 1-4 alkyl; R 7 is selected from the group consisting of hydrogen, fluorine and C 1-4 alkyl Or X, X 1 , X 2 or X 3 ; where X is equivalent to (I) ′ a, X 1 is equivalent to (I) ′ b, and X 2 is ( I) ′ c and X 3 corresponds to (I) ′ d; R 3 is hydrogen or C 1-4 alkyl; or X or X 1 R 4 is hydrogen or C 1-4 alkyl; or X or X 1 ; R 9 is C 1-4 alkyl; R 10 is hydrogen, C 1-4 alkyl , C 3-6 cycloalkyl or C 3-6 cycloalkyl C 1-3 alkyl; R 11 is haloC 1-2 alkyl; n is 1 or 2] The present invention relates to intermediates used in these production methods, pharmaceutical compositions containing them, and their use in therapy as serotonin (5-HT), dopamine (DA) and norepinephrine (NE) reuptake inhibitors. |
| priorityDate | 2007-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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