| abstract |
The present invention relates to a compound of formula (I): [Chemical 1] , And pharmaceutically acceptable salts or tautomers thereof, which are inhibitors of poly (ADP-ribose) polymerase (PARP), and thus cancer, inflammatory diseases, reperfusion injury, Treatment of ischemic symptoms, stroke, renal failure, cardiovascular disease, non-cardiovascular diseases, diabetes, neurodegenerative diseases, retroviral infections, retinal damage, skin aging, and UV-induced skin damage, and cancer It is useful as a therapeutic chemical sensitizer or radiosensitizer. |