http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010535808-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-16 |
| filingDate | 2008-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2010535808-A |
| titleOfInvention | Preparation of synthetic nucleosides by π-allyl transition metal complex formation |
| abstract | The present invention provides a highly regioselective and stereoselective method for preparing synthetic nucleosides. a) preparing a bicyclic amide derivative; and b) reacting the bicyclic amide derivative with a nucleobase, heterocyclic base, or salt thereof in the presence of a transition metal catalyst to form a cyclopentenecarboxamide. And c) cleaving the carboxamide group from the cyclopentenecarboxamide to form a synthetic nucleoside, providing a method for the preparation of a synthetic nucleoside. The method according to the invention can be used for the synthesis of various antiviral agents, including Abacavir, Carbovir, and Entecavir, and derivatives thereof. |
| priorityDate | 2007-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 306.