abstract |
Provided are compounds of formula (III) useful for modulating an immune response, compositions comprising this compound and methods of using such compositions for treating diseases or disorders involving an immune response. In certain embodiments, the compounds of the invention are useful for the treatment of diseases or disorders involving transendothelial migration of T cells and activated T cells and the production of inflammatory cytokines from T cells and macrophages. Treatable diseases or disorders include joint diseases and rheumatic disorders, such as rheumatoid arthritis. [Selection figure] None |