abstract |
The present invention binds to RANTES and regulates and secretes (regulated up activation, normal T-cell expressed, and secreted) (RANTES, CCL5) chemokines in response to the activation expressed by normal T cells. A fully human monoclonal antibody that modulates the interaction with one or more of its receptors (eg, CCR1, CCR3, CCR4, and CCR5) and / or modulates the biological activity of RANTES and its Regarding fragments. The present invention also relates to the use of these or any anti-RANTES antibodies in the prevention or treatment of immune related diseases and the alleviation of one or more symptoms associated with immune related diseases. |