| abstract |
The present invention provides beneficial pharmacological properties, in particular, the following general formula (I) that suppresses the interaction between glycogen phosphorylase a and the GL subunit of glycogen-related protein phosphatase 1 (PP1). [Chemical 1] (Wherein R, X, Y and Z are as defined in claim 1) substituted arylsulfonylaminomethylphosphonic acid derivatives, tautomers, enantiomers, diastereomers, mixtures and salts thereof, and pharmaceutical compositions thereof Concerning use as a thing. |