http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010532472-A

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-00
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filingDate 2007-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2010-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2010532472-A
titleOfInvention Optical sensor for surface-enhanced Raman spectroscopy
abstract An optical sensor for use with a laser beam and a Raman spectroscopic detector to detect the presence or content of a chemical or biological substance contained in an analyte, said optical sensor comprising a single crystal The surface-enhanced Raman scattering is enhanced by a strong local electric field formed by including a noble metal nanowire and formed at a contact point between the noble metal thin film and the noble metal nanowire or between the noble metal nanowires. The surface-enhanced Raman spectroscopic optical sensor of the present invention can be measured in-situ, has an adjustable hot spot, has the advantages of high reliability and reproducibility, and improves the sensitivity of the sensor The mechanical structure of the single noble metal single crystal nanowire and the polarization direction of the laser beam are optimized, and the sensitivity, selectivity, and diffraction intensity are high. In addition, the optical sensor for surface-enhanced Raman spectroscopy of the present invention has an advantage that it can be used as a biosensor or a disease diagnosis sensor as well as a chemical substance detection sensor by forming a nano-biohybrid structure on the surface of a noble metal nanowire. [Selection] Figure 17
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