| abstract |
The present invention comprises (a) a pharmaceutically acceptable biodegradable material, and (b) inoculated with said biodegradable material, and (i) a fibroblast, (ii) a fat-derived cell, or Publishes a tissue engineered tendon implant comprising (iii) a seed cell selected from the group consisting of a mixture of fibroblasts and adipose-derived cells of 1: 1000 to 10,000: 1. The aforementioned implant is obtained by mixing seed cells with a pharmaceutically acceptable biodegradable material to obtain a seed cell-biomaterial complex, and then culturing the complex in a bioreactor. The implant of the present invention is useful for repairing tendon defects. |