| abstract |
A compound of formula (I), or a pharmaceutically acceptable salt, solvate or ester thereof, is a CB 1 receptor mediated disease or condition (eg, metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and Useful for the treatment of psychosis, addiction (eg, smoking cessation), gastrointestinal disorders, and cardiovascular conditions. In one embodiment of the invention, at least one selective CB 1 receptor antagonist compound of formula (I) as described above or a pharmaceutically acceptable salt, solvate or ester thereof, and a pharmaceutically acceptable A composition comprising a carrier is also provided. |