abstract |
The present invention relates to a transglutaminase inhibitor containing epigallocatechin gallate (hereinafter referred to as EGCG). More specifically, the present invention relates to a transglutaminase inhibitor containing EGCG for inhibiting the action of transglutaminase, whose overexpression is involved in the pathological mechanism of the disease, and these novel uses. The present invention provides a transglutaminase inhibitor and a method for inhibiting transglutaminase containing EGCG as an active ingredient. The novel method for inhibiting transglutaminase using EGCG according to the present invention is a safe method that can be easily applied to a subject having a disease in which transglutaminase is overexpressed without side effects, thereby obtaining the effect of inhibiting transglutaminase. Can do. |