| abstract |
The present invention relates to a composition for the treatment, prevention, delay of its onset and / or delay of its development of a disease or condition in which activation, differentiation and / or proliferation of one or more cell types is beneficial. And providing a method. These compositions and methods include cells incubated with hydrogenated pyrido [4,3-b] indoles such as dimebon and / or hydrogenated pyrido [4,3-b] indoles such as dimebon. In certain embodiments, these compositions and methods also include growth factors and / or anti-cell death compounds. The present invention relates to a method for activating a cell, a method for promoting cell differentiation, by incubating the cell with one or more hydrogenated pyrido [4,3-b] indoles or pharmaceutically acceptable salts thereof, Also provided are methods of promoting cell proliferation. The cells are also incubated with one or more growth factors and / or anti-death compounds. |