| abstract |
The present invention provides compounds of formula I [Chemical 1] (Wherein R 1 ; R 2 ; R 3 ; R 4 ; R 5 ; R 6 ; Z; A; B; E; X; Q; J; V; G and M are described in the claims) The compound has a different meaning). The compounds of formula I are valuable pharmacologically active compounds. They exhibit a strong anti-aggregating action on platelets and thus an antithrombotic effect and are suitable for the treatment and prevention of cardiovascular disorders such as thromboembolic diseases or restenosis. It is a reversible antagonist of platelet ADP receptor P2Y12 and is generally applied in the presence of unwanted activation of platelet ADP receptor P2Y12 or for healing or prevention aimed at inhibition of platelet ADP receptor P2Y12 be able to. Furthermore, the invention relates to a process for the preparation of compounds of formula I, in particular their use as active ingredients in medicine and pharmaceutical formulations containing them. |