| abstract |
[Summary] The compounds of the present invention can be used in mammalian cancers, particularly human cancers such as, but not limited to, malignant melanoma, glioblastoma, ovarian cancer, pancreatic cancer, prostate cancer, lung cancer, breast cancer, kidney cancer, cervical Cancer, metastasis of primary tumor site, myeloproliferative disease, leukemia, papillary thyroid cancer, non-small cell lung cancer, mesothelioma, hypereosinophilic syndrome, gastrointestinal stromal tumor, colon cancer, hyperproliferation leading to blindness Diseases characterized by various diseases such as various retinopathy, rheumatoid arthritis, asthma, chronic obstructive pulmonary disease, mastocytosis, mast cell leukemia, c-Abl kinase, its oncogenic genotype, its abnormal fusion protein and its polymorph Applications are found for the treatment of diseases caused by or by c-Kit kinase, its oncogenic genotype, its abnormal fusion proteins and its polymorphs. [Selection figure] None |