Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-08 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-44 |
filingDate |
2008-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2010-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2010524938-A |
titleOfInvention |
Novel opiate reduction using catalytic hydrogen transfer reaction |
abstract |
An improved opiate synthesis scheme is provided. Improvements to the oxidation of oripavine and oripavine derivatives include the in situ formation of peroxyacids required to oxidize the oripavine and oripavine derivatives to form intermediates. Improvements to the reduction of the intermediates to form oxycodone and oxycodone derivatives include reducing the use of hydrogen transfer reagents. These improvements allow the generation of oxycodone and oxycodone derivatives without isolating intermediates, which provides a one-pot synthesis method. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015524407-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015524406-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016534999-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S58103490-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017502990-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111205296-A |
priorityDate |
2007-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |