http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010524937-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-08 |
filingDate | 2008-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2010-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2010524937-A |
titleOfInvention | Triazole derivatives that are SMO antagonists |
abstract | The present invention provides a method of treating or preventing a condition that can be ameliorated by Smo antagonism, wherein the method comprises an effective amount of a compound of formula I, or a compound of formula I: [Chemical 1] [Wherein, two of X, Y, and Z represent nitrogen atoms, the others represent oxygen atoms; R 1 and R 2 together with the atoms to which they are attached, 1 Represents a cyclobutyl ring optionally substituted with 2 fluorine atoms, R 3 represents hydrogen or a fluorine atom; or R 1 represents methyl and R 2 represents a methyl or fluorine atom , R 3 represents a fluorine atom] Alternatively, comprising administering to a patient in need thereof a composition comprising a pharmaceutically acceptable salt or solvate thereof. |
priorityDate | 2007-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.