abstract |
There is provided a fused heterocyclic compound according to formula (1): wherein R 1 , R 2 , R 3 and m are as defined herein. The provided compounds and pharmaceutical compositions thereof include various conditions in mammals, including humans (eg, pain, inflammation, cognitive impairment, anxiety, depression, etc., but these are non-limiting examples. Is useful for the prevention and treatment of In one embodiment, the compounds, pharmaceutical compositions and methods provided herein are a series of conditions in mammals (eg, pain of various origins or etiologies such as acute, chronic, inflammatory and neurogenic Useful for treating, preventing or ameliorating sexual pain, toothache and headache (eg, but not limited to migraine, cluster headache and tension headache). |