abstract |
The present invention relates to insulin-like growth factor binding of insulin-like growth factor I (IGF-I) or analogues thereof for use in the treatment of patients suffering from premature, very premature and / or very preterm birth complications. A composition comprising in combination with a protein (IGFBP) or analog thereof, wherein the combination has a molar ratio of IGF-I to IGFBP that is lower than equimolar, preferably in the range of 1:20 to 1: 3.33. And a method of treating a patient suffering from premature, very premature and / or very preterm complications. |