http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010524003-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate | 2008-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2010524003-A |
| titleOfInvention | Biomarkers and methods for determining sensitivity to vascular endothelial growth factor receptor-2 modulators |
| abstract | A method for predicting the likelihood of a mammal responding therapeutically to a method of treating cancer comprising administering a VEGFR-2 modulator or a dual VEGFR-2 / FGFR-1 modulator comprising: A method comprising: (a) measuring the level of FGF2 in the mammal; (b) FGF2 in the sample to allow assignment of the sample to a member of either the FGF2 positive class or the FGF2 negative class. Comparing the level with a standard, or comparing the level of FGF2 in a sample with a standard, where the assignment of a mammal to a class of FGF2-positive samples or a determination that a mammal has an elevated level of FGF2 It shows an increased likelihood of responding therapeutically to cancer treatment. In addition to kits containing these methods, methods for predicting whether a mammal has received an effective amount of a VEGFR-2 modulator or a dual VEGFR-2 / FGFR-1 modulator are also disclosed. |
| priorityDate | 2007-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 550.