http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010523623-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 |
| filingDate | 2008-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2010523623-A |
| titleOfInvention | Pyrazole derivatives as P2X7 modulators |
| abstract | The present invention relates to a compound of formula (I): [Where: R 1 represents C 1-6 alkyl or C 3-6 cycloalkyl, any of which may be substituted with 1, 2 or 3 halogen atoms; R 2 represents hydrogen, halogen, C 1-6 alkyl or C 3-6 cycloalkyl, and each of the C 1-6 alkyl or C 3-6 cycloalkyl is 1, 2 or 3 halogen atoms. May be substituted] It is related with the compound shown by these. The pyrazole compound of formula (I) or a salt thereof modulates P2X7 receptor function and can antagonize the effect of ATP at the P2X7 receptor (P2X7 receptor antagonist). The invention also relates to the use of such compounds or salts, or pharmaceutically acceptable salts thereof, in the treatment or prevention of disorders / diseases mediated by P2X7 receptors, such as pain, inflammation or neurodegenerative diseases. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014520880-A |
| priorityDate | 2007-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 288.