| abstract |
The present invention provides novel anthranilic acid derivatives that are effective as potential anticancer agents. More particularly, the present invention relates to novel anthranilic acid derivatives of general formula 8 wherein R ′ = alkyl-2methoxyphenylpiperazine (or) benzyl, R = 2mthoxyphenyl, piperazine, 2-pyridylpiperazine, 2- Pyrimidylpiperazine, 4-quinazolinylpiperazine, 9H-9-fluorenylamine, 4-[(2 {amino-5- (methoxy) -4-[(phenylmethyl) oxy] phenyl} carbonyl) hexahydro-1 -Pyrazinyl], and [(4 [2 amino-4- (benzyloxy) -5-methoxybenzoyl] aminophenyl) sulfonyl] -4-benzamine; X = H (or) pyrazine-2-carbonyl. The present invention also provides a process for preparing novel anthranilic acid derivatives of general formula 8 that are effective as potential anticancer agents. [Chemical 1] |