| abstract |
PROBLEM TO BE SOLVED: To provide a compound of formula I for use in the treatment and prevention of a disease in which inhibition, control and / or regulation of mitotic motor protein, in particular, mitotic motor protein Eg5 plays a role, and use thereof, as well as these compounds A pharmaceutical composition is provided. A compound of formula (I) wherein E, R 3 , R 4 , R 5 , X, Y, W, Q 1 , Q 2 , Z, s and m are as defined in claim 1 Has meaning) can be used, inter alia, for the treatment of tumors. [Selection figure] None |