| abstract |
[Chemical 1] The present invention relates to compounds of formula (I), methods of making these compounds, their compositions, intermediates and derivatives, as well as, but not limited to ankylosing spondylitis, atherosclerosis, arthritis (rheumatoid arthritis, Infectious arthritis, pediatric arthritis, psoriatic arthritis, reactive arthritis, etc., bone-related diseases (including those related to bone formation), breast cancer (including those not responsive to anti-estrogen therapy), cardiovascular System disorders, cartilage related diseases (such as those related to cartilage injury / reduction, cartilage degeneration and cartilage formation), cartilage dysplasia, chondrosarcoma, chronic back injury, chronic bronchitis, chronic inflammatory airway disease, chronic obstructive pulmonary disease, Diabetes, energy homeostasis, gout, pseudogout, dyslipidemia, metabolic syndrome, multiple myeloma, obesity, osteoporosis, osteogenesis imperfecta, osteolytic bone metastasis, bone Sclerosis, osteoporosis, Paget's disease, periodontal disease, polymyalgia rheumatica, Reiter's syndrome, repetitive strain injury, hyperglycemia, the method relates to the treatment of conditions which may be mentioned increase in blood glucose level, and insulin resistance. [Selection figure] None |