| abstract |
The present invention relates to compounds of the structural formula Wherein R 1 is —H or —C 1 -C 3 alkyl, R 2 is —H, —C 1 -C 4 alkyl, —C 1 -C 3 alkyl-CF 3 , phenyl, and R 3 is selected from the group consisting of pyridinyl and R 3 is —H, —C 1 -C 4 alkyl, —C 1 -C 3 alkyl-O—CH 3 , —CH 2 -cyclopropyl, —CH 2 —C═. CH 2, -CH 2 CH 2 - (2-F- phenyl), and one to two fluorine is selected from the group consisting of phenyl substituted, provided that, R 1 and R 2 are each are H In this case, R 3 is —C 1 -C 4 alkyl, —C 1 -C 3 alkyl-O—CH 3 , —CH 2 -cyclopropyl, —CH 2 —C═CH 2 , —CH 2 CH 2 — ( 2-F-phenyl), and a phenyl substituted with 1-2 fluorines It is selected from the group consisting of Le), or relates to the stereoisomers and pharmacologically acceptable salts. |