| abstract |
The present invention relates to a pharmaceutical composition having thixotropy capable of continuously transitioning to a gel / sol / gel state by changing the viscosity by an externally applied physical force or the like at an isothermal temperature. The thixotropic pharmaceutical composition of the present invention comprises an active substance having pharmacological activity, a biocompatible thickener having a predetermined thixotropy, and a selective hydrophilic thickener, and the viscosities of the compositions are compared. Changes quickly and within an appropriate range, making it easy to meter the drug to be administered, thereby enabling the patient to administer an accurate amount of the drug, not only making the patient more adaptable, but also Easy. |