abstract |
The present invention provides a method for reducing the side effects of tramadol. Accordingly, in one embodiment, the present invention provides a method of reducing the incidence of side effects related to newly discovered sexual function in human men taking tramadol material. The method includes administering a phosphodiesterase inhibitor to a man taking the tramadol material. The present invention also provides a pharmaceutical composition. In one embodiment, the composition comprises a tramadol material and a phosphodiesterase inhibitor. The present invention further provides a kit. In one embodiment, the kit includes a tramadol material and a phosphodiesterase inhibitor. |