| abstract |
The present invention provides a water soluble pharmaceutically active ingredient from an aqueous phase comprising an occlusive backing layer, a central device facing the skin to release the agent, an adhesive layer concentrically surrounding the dosing device and a removable protective film. It relates to a transdermal therapeutic system for controlled release. The device is made of a fixed solid phase and a liquid phase containing an active ingredient in an aqueous solution, and the solid phase is formed of a solid material having a fleece or sponge-like structure. |