abstract |
The present invention relates to compounds containing a 1,3-dioxane moiety, their pharmaceutical compositions and the use of said compounds and compositions for the modulation of thromboxane A2 or peroxisome proliferator activated receptors. The compounds, analogs, and pharmaceutically acceptable salts thereof, and pharmaceutical compositions can be used in the treatment and prevention of cancer. In one embodiment, the compounds of the present invention have thromboxane A2 inhibitory activity and / or peroxisome proliferator activated receptor activation activity, and therefore the compounds of the present invention are useful as therapeutics as antitumor agents. possible. |