| abstract |
The present invention relates to a drug comprising an unsaturated aliphatic amino acid derivative of the general formula (I), and pharmaceutically acceptable acid addition salts thereof. Wherein X is oxygen or NH, Rn is independently hydrogen or (C 1 -C 6 ) alkyl optionally substituted with halogen, R 1 is hydrogen, fluorine, chlorine or bromine or where substituted with one or more halogen atoms, if CF 3 or CHF 2 or necessary (C 1 -C 6) alkyl, (C 1 -C 6) alkenyl or (C 1 -C 6 ) Alkynyl and R is hydrogen or (C 1 -C 6 ) alkyl or (C 3 -C 6 ) cycloalkyl optionally substituted with one or more halogen atoms, and Ra and Rb Are independently hydrogen, (C 1 -C 6 ) alkyl or (C 1 -C 6 ) acyl, and Ra and Rb are hydrocarbonated rings containing 4 to 6 carbon atoms, and n is To 14 of an integer). |