| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate |
2008-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2010-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2010515717-A |
| titleOfInvention |
Diagnosis and treatment of Alzheimer and other neurodementia disorders |
| abstract |
Shields Aβ (21-37) from proteolytic digestion when it binds to the dimeric form of Ab with higher affinity than to the monomeric form of Ab and binds to an Aβ polypeptide comprising Aβ (21-37). An isolated monoclonal human anti / 3 amyloid antibody is provided. The antibody has been shown to inhibit fibrosis and reduce plaque size in vivo and not bind to the brain vessel wall. Thus, antibodies are useful in the treatment and prevention of Alzheimer's disease and other neurodementia diseases in human and veterinary medicine. Also provided are methods for detecting or measuring the progression of neurodementia disease. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015111430-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10942190-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013083644-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014529087-A |
| priorityDate |
2007-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |