abstract |
The present invention provides compounds useful for increasing the production of cellular ATP-binding cassette transporter ABCA1 in mammals and methods of using such compounds in the treatment of coronary artery disease, dyslipidemia and metabolic syndrome To do. The present invention also relates to methods for preparing such compounds and pharmaceutical compositions containing them. In one embodiment, the present invention relates to a method for using a compound of formula I in the treatment of a disease or condition in a mammal that can be treated with a compound that increases serum HDL-C levels, the method comprising: Administration of a therapeutically effective dose of a compound of I to a mammal in need thereof. |