| abstract |
Use of a hypertonic solution composition for the manufacture of a medicament for promoting wound healing used during the perioperative period, said composition comprising sodium chloride, sodium bicarbonate, potassium chloride, magnesium sulfate, calcium chloride and 1.5% to 6.9% (w / v) of one or more substances selected from calcium gluconate and 3% of one or more substances selected from hydroxyethyl starch, dextran, carboxymethyl starch, polyvinylpyrrolidone and gelatin derivatives It consists of ˜18% (w / v) and the remaining amount of normal injection solution. In the composition, sodium chloride is 1.5% (w / v) or more and the sodium ion concentration is 6.9% (w / v) ) Satisfying a condition that is equal to or lower than the concentration corresponding to the concentration of sodium ions in the sodium chloride solution. The hypertonic solution composition is instilled as an infusion solution before, during and after surgery, and the dosage is 100-1500 ml / person / day, which can promote wound healing after use and is safe to use. There is an advantage that it is convenient and can be widely used for various surgical wounds or wounds (surfaces) and anastomosis. [Selection figure] None |