http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010512783-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
| filingDate | 2007-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2010512783-A |
| titleOfInvention | Methods for screening metabolites essential for microbial growth |
| abstract | The present invention relates to a method for screening metabolites essential for the growth of microorganisms using metabolic flux analysis, and more specifically, after selecting a target microorganism and constructing a metabolic circuit model of the selected microorganism, the construction is performed. Inactivate the consumption reaction formula of each metabolite in the metabolic circuit model, analyze the metabolic flux, select the metabolite essential for the growth of the microorganism, and then define each metabolite defined as flux sum (Φ). The present invention relates to a method of screening the metabolites essential for the growth of microorganisms by confirming the selected metabolites using the degree of utilization. According to the present invention, metabolite metabolites essential for the growth of microorganisms and genes involved in the essential metabolites can be easily screened, and the metabolic utilization (flux sum: Φ) of the essential metabolites can be reduced. Can be used to predict drug target genes of pathogenic microorganisms by deleting genes associated with metabolites screened by the above method. |
| priorityDate | 2006-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 950.