| abstract |
The present teachings are compounds of formula (I) And with respect to pharmaceutically acceptable salts, hydrates and esters thereof, Ar, R 1 , R 2 , R 3 , p and X are as defined herein. Further, the present teachings provide a process for making the above-described compounds and pharmaceutically acceptable salts, hydrates and esters thereof, a method for treating a pathological condition or disorder, or a method for alleviating symptoms thereof, a pharmaceutical Also provided are methods of using the above-mentioned compounds, including pharmaceutically acceptable salts, hydrates and esters. The compounds may be useful in modulating the activity of ion channels, including treating various conditions associated with an abnormally regulated state of one or more voltage-gated calcium channels. |